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PEMF and myelinated neurons
This post was inspired by an MD using PEMF who was convinced that PEMF was enabling saltatory conductance by myelinated fivers. In the original experiments of Luigi Galvani and his frog legs in which nerves were impaled with electrodes ]1] This post is written for MDs and other with a very good background in…
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Cry2 and transcranial magnetic stimulation
Most of this post is about work by Dr Rachel Sherrrard’s group at Sorbonne Université in Paris France and collaborators from around the world. The featured image is from Protein Atlas showing Cry2 staining in the cerebellum. The very obviously striated staining for Cry2 in the cerebellum and long with biochemical proof of Cry2 involvement…
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NeuroEM for Alzheimer’s
This post explores a “mechanistic” mouse study of NeuroEM’s device for treating Alzheimer’s Disease. [1] It should be noted that the Assisi radio frequency PEMF device was designed to target the Ca2+ calmodulin interaction. The Neuro EM device appears to target complex IV of the mitochondrial electron transport chain. A diurnal component of very…
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Re5 Transcranial PEMF
This post reviews two trans cranial PEMF devices used in the literature: the Re5 uses very low frequency PEMF to treat Parkinson’s Disease and the NeuroEM uses radio/microwave EMF to treat Alzheimer’s Disease. The former acts by increasing EPO in the CSF. The latter increases cognitive and mitochondria performance while decreasing Aβ aggrefation.
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electrical stimulation and hind limb unloading
Many PEMF practitioners use PEMF when an animal, including humans, has an injured limb and loss of use of the associated skeletal muscle. Some may argue that PEMF resembles electrical stimulation via Faraday’s Law of Induction. PEMF seems to act on the ERK signaling cascade in cultured myoblasts. [1] Electrical muscle stimulation in a…