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Presenillin, often referred to by its gene name PSEN1, is a subunit in the gamma secretase complex, which cleaves integral membrane proteins. This image was obtained from the UniProt link. The UniProt and Go annotations categorize PSEN1 as a mult-pass membrane protein found in all stages of endosomes,axon projections, and the synapse. The structure…

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This post attempts to cover two publications of the Cl C7 exchanger in the choroid plexis of the brain. Links are given for figures that might be copyrighted. The intent is to provide an explanation as to what is going on in the open access journal articles.