PEMF and heavy metal detox

Many are saying that PEMF can help the body detoxify itself of heavy metals. indeed, some early research proposed some complicated mathematical models by which PEMF causes Ca²⁺ to resonate and other wise move about the cell. These mathematical models can be used to ask whether PEMF is shaking loose the metal by way of the metal or the biomolecule the metal is bound to. The answer impacts the choice of PEMF device.

Shaking loose Ca²⁺ [1] and toxins via Truly Heal

Dr. Richard Funk is a leader in the biology of PEMF. He and Manfred Fähnle coauthored a very nice review on the role of PEMF in causing and/or treating neurological diseases. [1] For some reason, Ca²⁺ homeostasis was front and center. Resonance Ca²⁺ was a mechanism PEMF interaction with neurons. The new term that was introduced, ion cyclotron resonance, lead to the speculation that PEMF may be fine tuned to get more than just Ca²⁺ ions moving. The evidence of PEMF and heavy metal detox is poor. This youtube video by Truly Heal. Metals “dogging on” cell membranes is mentioned a lot as is shaking things up. Truly Heal mentions many of the same binders as mentioned on this site. does not really go into the science, but seems to touch on a truth of Ion Cyclotron Resonance that might be true for Ca²⁺ and divalent heavy metals. Were parts of the cell being shaken or the heavy metal itself? The Funk and Fähnle review leg the way to a new term, “resonance” that allows for the shaking cell parts and/or the heavy metals that are “dogging on.”

Ion resonance, f_c=qeB/m2π [2]

Aspects of this narrative are extremely confusing. Perhaps is best to keep in mind that scientists can use PEMF to measure the mass of charged particles. This implies that the right combination of frequency and magnetic field in our PEMF device that shake up the cell heavy metal interaction.

what the terms mean [2]

Ion cyclotron resonance is the movement of charged particles in a magnetic field. q is the charge of the particle. Lowercase “e” is the elementary charge, or the charge carried by a single proton. f is the angular frequency. The 2π component converts rad per second to circular cycles per second. B_dc is the magnetic field produced by direct current. As The larger the mass of the particle, the lower the characteristic frequency f_c.

An abbreviated table and equations [2]

This table has been edited for elements of interest on site. Is it the charged particle itself or the unpaired electron that is responding to the magnetic field? Unpaired electrons tend not to exist in biology for very long. Ca²⁺ has no unpaired electrons, Metallic Ca•• has two unpaired electrons and does not last long in water long due to reactivity! “Sulfur 4” and “Sulfur 6” likewise do not exist in biology unless those unpaired electrons are paired with something else. Hydrogen sulfide (H₂S) and the sulfate ion (SO₄^-2 is another example. In so many ways, this Blanchard and Blackman table could be better explained.

What confuses me by this model

• While ion cyclotron resonance might be used to measure the mass/charge ratio in the vacuum of a mass spectrometer, there is other junk in the cell that might impede resonance.
• I don’t get the charges attached to various atoms. Those electrons are used to form bonds with other atoms such that the mass o the particle is increased.
• Will other particles in the cell keep the targeted particles from resonating?
• How close to or above 1 permits resonance in this n=f_c/f_ac
  

The truly maddening definition of resonance

A YouTube phospholipid bilayer bilayer in water video note the thermal motion. Phosphatidyl choline has a magnetic moment. This is a DOPC molecular dynamics video, snippets are shown in the image below.

Isolated spinach plasma membranes [3]

The Ca²⁺ pump intro

In their introduction Bauréus and coauthors discussed the importance of the cytosolic Ca²⁺ ATPase in maintaining the very low concentrations of intracellular concentration is maintained by the plasma membrane Ca²⁺ pump (Ca²⁺-ATPase). The plasma membrane of spinach cells also contains a Ca²⁺-ATPase. In this particular system radioactive ⁴⁵Ca²⁺ was added outside these spinach plasma membrane vesicles. Unlike animal cells in which the Ca²⁺-ATPase is only expressed mostly in the endoplasmic reticulum (ER), members of the Ca²⁺-ATPase are expressed in the ER, cell membrane, vacuoles, Golgi, and so on. ref. In the Funk review [1] cell membrane, receptors, and protein channels act as levers or antenna activated by the resonance phenomena.

Data and cartoons

summary of figures [3]

• Temperature influenced the Ca²⁺ flux.
• Fig 4 illustrated changes in the “Bessel function” as B_AC/B_DC and n=f_c/f_ac were varied.
• Fig 5 When B_AC/B_DC =0.07, frequencies below 20 Hz decreased the relative Ca²⁺ efflux.
• Fig 6 When frequency was set at 24 Hz, B_AC/B_DC less than 2 decreased the relative Ca²⁺ efflux.
• Fig 7 When frequency was set at 16.7 Hz, B_AC/B_DC had no influence on the relative Ca²⁺ efflux.
• Fig. 8 [3] describes how complicated even a “simple” membrane can be. . The ratio of the mean efflux of Ca ²⁺ through the membrane was plotted as a function of the frequency for a fixed amplitude of the static magnetic field B_DC of 37 μT and B_AC/B_DC ratio of 0.7. They scanned the frequency interval of 18 to 34 Hz. Three Gaussian peaks of equal width were identified. At 20 and 24 Hz Ca²⁺ efflux was below the baseline. At 30 Hz Ca²⁺ efflux was above the baseline.

PC12 cells, a model for neurons [4]

Scholarly Community Encylopedia has a nice piece on the origin of PC12 cells from a rat pheochromcytoma cell line. This neuron like cell line may sometimes produce neurite out growths (NO, not to be confused with nitric oxide). Nerve Growth Factor NGF is required to produce these n.o. Note that activated/phosphorylated, Akt is involved in neurite out growth.

• When frequency was held constant at 45 Hz, n.o. decreased as B_AC increased from 77 to 200 mG
• When frequency was held constant at 45 Hz, n.o. increased as B_AC increased from 100 to 468 mG
• When frequency was held constant at 45 Hz, n.o. did not change as B_AC increased from 20 to 50 mG

Is Mg²⁺ and/or “H⁺” resonating in PC12 cells?

This post is neglecting studies at 25 Hz in which Blackman and coauthors attempted to bring other ions into resonance. Much in the discussion was made of the cations H⁺ and Mg²⁺, neither of which always exist as free ions in biological systems. When these ions are bound, do they have their atomic mass m or their molecular mass? There are some biological realities that need to be addressed:

C. Proteins have side chains of acidic groups that can lose H⁺ to water to form H₃O⁺.

Ion cyclotron resonance, making heavy metals move?

• The equation fc=qeB/m2π [2] tells us that size matters as does the charge when it comes to the resonance frequency.
• Changing the frequency and the magnetic field affected Ca²⁺ homeostasis in spinach cell membranes. [3] Something very interesting was going on. The magnetic field was so weak, probably only Ca²⁺ was being “shaken up”: to use Truly Heal terminology.
• When the frequency was held at 45 Hz, changing the magnetic field affected neurite out growth in a neuron like PC12 cells. [4] The affect could not be attributed to Ca²⁺ ICR theoretically.

Playing around with numbers

It is difficult to find the magnetic field density of the settings for the Semi-10. An Australian company sells what appears to be the Semi-10. This company reports the magnetic field density in Gauss. One Telsa (Science International unit) is 10,000 Gauss. Using SI units, e is 1.602176634×10⁻¹⁹ C. T is, SI units, kg⋅s⁻²⋅A⁻¹. Force is part of the units, force being measured in Neutrons, with the mass in kg… Chemists like to measure the mass of particles in Daltons. A carbon atom (with 12 neutrons and protons) has a mass of 12 Daltons. A Dalton is   1.66053906892(52)×10⁻²⁷ kg. Testing my spread sheet, at 205 mG and 45 Hz, the m/z is around 7. Going up to 575 mG and the same 45 Hz gives a m/z of 19.6 ish. Bringing the Hz down to 20 /sec brings the m/z up to 45 Da per charge. Bringing the Hz down further to 1/sec and keeping the magnetic field at 575 mG brings the m/z up to 800 something.

var.	Omi body mat	Omi body mat	Bremer mat	Bremer mat	Bremer mat	Bremer mat	study [2]	study [3]	study [4]	Healthy Balance mat	Healthy Balance mat	Healthy to Be ClinicDuo
freq,Hz	1	99	33	33	1	30	45	34	45	0.5	1000	50
magnetic field ,T	0.0022	0.0022	0.000035	0.000015	0.0003	0.0003	0.0000575	0.000037	.0000366	0.001	0.001	0.6503
mass to charge m/z	3.38 kDa	34Da	16 Da	7 Da	5kDa	154 Da	20	17 Da	12.5 Da	30.7 kDa	15.4 Da	200kDa

This Health Mat site compared various PEMF mats whose actual field intensities for the body laying on top of the mat are anyone’s guess. Heathywave Pro (HWP) PEMF. “It can be seen that the Healthy Wave Multi-Wave Mat (aka Bremer) allows 30 different frequencies adjusted from 1 up to 30 Hz, and 10 intensity levels from very low intensity (0.3 Gauss), up to a maximum of 3 Gauss.”

Some of the complexities of studies {2] and [4] have been ignored. Mass to charge, m/z or m/q, ratios of 20 and 12,5 are consistent with physiological divalent cations.

These PEMF mats really do not put out intense magnetic fields.

Sleeping on top of one will not expose a sore shoulder note physically touching the mat in the same way a set of coils placed directly on the shoulder. It is curious that lower frequency fields can theoretically larger molecules simply because of the time it takes to

Arthur Pilla, inventor of the Assisi Loop discussed on this site, had these issues with the simple ion cyclotron resonance equations:

• The viscosity of the biological fluid is not addressed.
• the diameter of the cyclotron orbit may be larger than the total size of the biological target itself
• The rotation of the target protein and the shape of the active sites may change in a magnetic field.
• Citing previous work: “the induced electric field from an AC magnetic field in the order of 100 mT with frequency below 100 Hz is not expected to produce significant bioeffects”

Concluding thoughts

WagnaWave (MW) was only willing to share the Magnetic field and frequency of the highest setting for obvious proprietary reasons. They were wiling to share the setting 1 frequency of 20 Hz. Just for discussion a fabricated value of 0.01T was used.

Follow up, shaking Hg²⁺ out of fish products

If any of this is valid, the FDA has tested for mercury in canned fish products. The mean values are around 0.03ppm. We may buy large amounts of the same batch of canned tuna at local grocery stores. We do not have to worry about disposal of a heavy metal in testing various settings of the Semi-10 for “shaking Hg²⁺ out of tuna. Many companies claim that their PEMF devices aid in detoxification. Test strips are available from Ebay that can detect 2-80 ppb.

References

1. Funk RHW, Fähnle M. A short review on the influence of magnetic fields on neurological diseases. Front Biosci (Schol Ed). 2021 Dec 3;13(2):181-189. free paper
2. Blanchard JP, Blackman CF. Clarification and application of an ion parametric resonance model for magnetic field interactions with biological systems. Bioelectromagnetics. 1994;15(3):217-38. Sci-Hub free paper
3. Bauréus Koch, C. L. M., Sommarin, M., Persson, B. R. R., Salford, L. G., & Eberhardt, J. L. (2003). Interaction between weak low frequency magnetic fields and cell membranes. Bioelectromagnetics, 24(6), 395–402. Sci-Hub free paper
4. Blackman CF, Blanchard JP, Benane SG, House DE. Empirical test of an ion parametric resonance model for magnetic field interactions with PC-12 cells. Bioelectromagnetics. 1994;15(3):239-60. doi: 10.1002/bem.2250150307. Erratum in: Bioelectromagnetics 1995;16(2):145. PMID: 8074739. Sci-Hub free paper