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Desmin and mitohormesis
Hormesis is a two-phased dose-response relationship whereby low-dose exposures have a beneficial effect and high-doses toxic. Pulsed ElectroMagnetic (very low) Frequency (PEMF) mitohormesis is the slight generation of reactive oxygen species that activates the transient receptor potential C1 (TRPC1) Ca2+ channel. Ca2+ signaling and mitochondrial adaptations are shared between magnetic fields and endurance training in…
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PEMF and atherosclerosis
This post is an ad for a Moodle.com course I’d like to create explaining this PEMF publication. I’ve taken a few online courses and learned so much from the discussion than from the actual course material. This post previews what I know about the methods used to generate the hypothesis that PEMF ameliorates the…
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28 kHz PEMF mitochondria
This post follows a mitochondria PEMF study partially funded by Hofmeir Magnetics Ltd, Reading, UK, the source of the device. The mitochondrial energetics work was performed by the Austrian not-for-profit organization Trauma Care Consult GmbH. The study sought to establish a mechanism. This study if very unique in the interrogation of various mitochondrial respiratory…
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PEMF and complex II
succinate dehydrogenase (SDH: SDHA-D), is made up of four protein subunits along with iron-sulfur (FeS) centers. Complex Portal links t the Swiss site UniProt.org. UniPort annotates the amino acid sites of proteins that interact with substrates and cofactors. Toda and coworkers 23023 investigated the effect of optimized extremely low frequency weak magnetic fields (Opti-ELF-WMF)…
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Red Light and mitocondria
Right light therapy is said to target cytochrome C oxidase, complex IV, of the mitochondria. Most complexes of the mitochondria contain functional groups that absorb one wavelength of visible light or another. Absorption of light may translate into increased membrane potential, which translates into more ATP. This post introduces the role of ATP in…