PEMF and drug resistance E coli cystitis
Cystitis is defined as a bladder infection, generally caused by a bladder infection. Ivan D’Agostino is an independent researcher out of Rome Italy. F Marcelli is affiliated with CRESO LLCs, 6830 Chiasso, Switzerland came up with a PEMF protocol to treat drug resistant E coli cystitis. The authors found some encouraging results in terms of a reduction in E coli counts in the urine. Some of the PEMF steps they used seem to be based on published studies. It really hard to pin anything tha resembles a mechanism in this study. Micro-Pulse ICES PEMF devices have a variety of protocols that are resented in this post. I think those that already own PEMF devices might give it a try for this condition in addition to standard of care and and an open minded healthcare provider.
Briefly what was done
For treatment, a sequence of signals (BSBI) was created, combining frequency, field intensity, waveform, application time, and pulsation time. The BSBI sequence underwent artificial intelligence processing ChatGPT 3, https://openai.com
The PEMF ion resonance generator can write signal sequences (combining frequency, field intensity, waveform, application time, and time per cycle), store them on a card, and emit them. Emitted sequences were from 1 to 80 Hz, with 30 wave forms, and signal intensity was from 1 to 100 µT at the source. Each LIE emitter weighs 125g and has a conical range starting from 5–6 cm up to 15 cm, with a depth of about 20 cm
- 148 females, aged 18 to 80 years
- diagnosed with chronic bacterial cystitis caused by drug-resistant E. coli,
- an experimental group (n = 74) with a sequence of electromagnetic fields, Click on this link for a table of times, frequencies, and magnetic fields. The authors claim to have used the “artificial intelligence” site ChatGPT to design the PEMF treatment. Emitted sequences were from 1 to 80 Hz, with 30 waveforms, and signal intensity was from 1 to 100 µT at the source.
- There were some 2mT/ 50Hz steps with undisclosed wave forms.
- For biohackers wishing to perform their own cystitis intervention, click here for the placement of the coils.
- Both groups were assessed at this study’s outset, 4 weeks after eight applications, and at 12 weeks for symptomatic presentation and laboratory parameters.
| reference | frequency | field strength | time | outcome |
|---|---|---|---|---|
| Oncul 2018 | 50 Hz | 1 mT | 2hr | messed up membrane surface charge. |
| Bayir 2015 | 20 Hz | 4mT | 6hr | 85% E coli growth inhibition |
| Al-Harbi 2018 | 0.1 to 1.0 Hz | 200 V/m | 90 min | 42.3% E coli growth inhibition |
D’Agostino 2024 | 50 Hz | 2 mT | 3 min | 2 of 13 PEMF steps, different wave forms, decrease in E coli in urine |
D’Agnostino 2024 cited other PEMF studies that addressed other issues with tissue inflammation and smooth muscle function. Some of the other 11 steps may have been vaguely based on these studies.
encouraging results
Click here for Table 6 E coli counts. The numbers seem to be coming down in the treatment group at at the end of the four week treatment and 12 weeks later. It is assumed that all parameters measured in this study were performed at standardized testing laboratories as no descriptions were given in the “Materials and Methods” section of the publication.
Biohackers, where to get a PEMF device
This post was going to contain instructions on how to test for E coli in urine. This crosses the line of practicing medicine. Work with someone or a lab licensed to perform E coli counts. This is where biohacking crosses the line of practicing medicine. If you are working with a holistic physician or naturopath, they may have a testing laboratory in mind to test progress..
Micropulse sells lower cost PEMF devices that should do no harm if used carefully.
| A9 | C5 | P2 | Omni 8 | all | ||||||||
| Time min | Freq pps | Wave form | Time min | Freq pps,off sec | Wave form | Time min | Freq pps,off sec | Wave form | Time min | Freq pps,off sec | Wave form | mode |
| 10 | 5 | +/- | 10 | 5100,5 1 | +/- | 10 | 5 | +/- | 10 | 5 | +/- | 1 |
| 10 | 100 | + | 2 | 100, 1 | + | 10 | 100 | + | 2 | 100→5 | +→+/- | 2 |
| 10 | 100 | – | 2 | 100,1 | – | 10 | 100 | – | 2 | 100→5 | -→+/- | 3 |
| 5 | 10,1 | +/- | 10 | rest | 1 | 3.92 | +/- | 4 | ||||
| 1 | 100→5 | + | 1 | 7.14 | +/- | 5 | ||||||
| 1 | 100→5 | – | 1 | 10.42 | +/- | 6 | ||||||
| 1 | 13.20 | +/- | 7 | |||||||||
| 1 | 16.95 | +/- | 8 | |||||||||
References
- Al-Harbi F.F., Alkhalifah D.H.M., Elqahtani Z.M., Ali F.M., Mohamed S.A., Abdelbacki A.M.M. (2018) Nonthermal control of Escherichia coli growth using extremely low frequency electromagnetic (ELF-EM) waves. Biomed. Mater. Eng. 2018;29:809–820. doi: 10.3233/bme-181025. [PubMed]
- Bayır E., Bilgi E., Şendemir-Ürkmez A., Hameş-Kocabaş E.E. (2015) The effects of different intensities, frequencies and exposure times of extremely low-frequency electromagnetic fields on the growth of Staphylococcus aureus and Escherichia coli O157:H7. Electromagn. Biol. Med. 2015;34:14–18. doi: 10.3109/15368378.2013.853671. [DOI] [PubMed] [Google Scholar]
- D’Agostino I, Marelli F.(2024) Chronic E. Col Drug-Resistant Cystitis Treated with a Sequence of Modulated Extremely Low-Frequency Electromagnetic Fields: A Randomized Study of 148 Cases. JClin Med. 2024 Apr 30;13(9):2639. PMC free paper
- Oncul S., Cuce E.M., Aksu B., Inhan Garip (2016) A. Effect of extremely low frequency electromagnetic fields on bacterial membrane. Int. J. Radiat. Biol. 2016;92:42–49. [PubMed]
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